Where hypertension happens

Where hypertension happens.

Essential hypertension, which accounts for 90%-95% of all cases of hypertension seen in the clinic, is also referred to as idiopathic hypertension, because we simply don't understand the cause(s). Although many theories have been advanced, in the current issue of the JCI, Gonzalez-Villalobos et al. present further evidence implicating the intrarenal renin-angiotensin system and take us one step...

Early Vision: Where (Some of) the Magic Happens

A recent study provides new insights into how the very different response characteristics of the main visual pathways from the eye to the brain may directly result from the presence or absence of a 'spike trigger-zone' in retinal bipolar cells.

Masked hypertension: where do we stand?

A mechanism for the formation of hippocampal neuronal firing patterns that represent what happens where.

The association of specific events with the context in which they occur is a fundamental feature of episodic memory. However, the underlying network mechanisms generating what-where associations are poorly understood. Recently we reported that some hippocampal principal neurons develop representations of specific events occurring in particular locations (item-position cells). Here, we investiga...

Where Syllogistic Reasoning Happens An Argument for the Extended Mind Hypothesis

Does cognition sometimes literally extend into the extraorganismic environment (Clark, 2003), or is it always “merely” environmentally embedded (Rupert, 2004)? Underlying this current border dispute is the question about how to individuate cognitive processes on principled grounds. Based on recent evidence about the active role of representation selection and construction in learning how to rea...